Nelson Mandela significantly impacted global human rights by championing anti-discrimination causes through organizations like the United Nations, where he advocated for sanctions against apartheid regimes. His leadership highlighted issues of racial and social inequality, influencing policies such as the Millennium Development Goals. Mandela's legacy continues through foundations and initiatives promoting education and AIDS awareness, setting precedents for international humanitarian efforts to combat injustice and inequality.

Harvey Milk advanced LGBTQ+ rights by championing anti-discrimination laws, organizing community coalitions, and using his platform as a San Francisco Supervisor to promote visibility and equality for gay people.

Hillary Clinton significantly impacted women's rights by co-founding organizations like Vital Voices and championing initiatives such as the U.S. National Action Plan on Women, Peace, and Security during her Secretary of State tenure. She advocated for equal pay legislation, reproductive rights, and education access globally, famously declaring in 1995 that "women's rights are human rights." Her legacy includes mentoring female leaders and influencing global gender equality policies.